Características clínico-patológicas de cáncer de mama en mujeres: un estudio de 1,840 diagnósticos

Abstract

Objective: To report the clinicopathological characteristics of women diagnosed with breast cancer (BC) who were treated at the Instituto Jalisciense de Cancerología (IJC), located in Guadalajara, Jalisco, during 2013-2017.

Materials and methods: Cross-sectional and analytical design whose data source was the clinical records and the electronic registry of the IJC. The following data from women with a confirmed BC diagnosis were included and analyzed: age, grade and histological variety, clinical stage reported by in situ (0), early stage (I-IIA), locally advanced (IIB-IIIC) and metastasis (IV) categories, as well as hormone receptor status. The women were classified into two age groups: <40 and ≥40 years, in order to compare the clinicopathological characteristics through statistical tests. Descriptive analysis of the data is presented.

Results: Data related to 1,840 diagnoses of BC were collected and analyzed; the average age of women at the time of diagnosis was 53.2 years. The most frequent clinicopathological characteristics were: locally advanced (53.1%), ductal (88.9%), moderately differentiated (60.1%) and Luminal A (31.6%); while 15% of the cases reported triple negative classification, mainly women <40 years (21.3%). Except for the histological variety (p <0.05), no significant differences were found between both age groups regarding the clinicopathological characteristics analyzed.

Conclusions: In Mexico, clinicopathological characteristics of BC have rarely been reported, which involve important clinical management and decision-making regarding the various therapeutic treatments. Therefore, the evidence presented here contributes to recognizing the clinicopathological profile of the women who sought cancer care at the IJC during 2013-2017, as well as being useful for developing other epidemiological studies to evaluate the impact on BC recurrence and the survival chances of women.