Efecto del consumo de margarina baja en grasas trans en la función de la insulina

Nicte Susana Alvarado Pérez; Jessica Lizeth Diez Larios; Alberto Jiménez Maldonado; Alin Jael Palacios-Fonseca Palacios Fonseca; Mario Del Toro Equihua; Joel Cerna Cortés

doi:10.19136/hs.a25n1.5945

Authors

Nicté Susana Alvarado Pérez University of Guadalajara
Jessica Lizeth Diez Larios University of Guadalajara
Alberto Jiménez Maldonado Autonomous University of Baja California
Alin Jael Palacios Fonseca University of Colima
Mario Del Toro Equihua University of Colima
Joel Cerna Cortés University of Colima

DOI:

https://doi.org/10.19136/hs.a25n1.5945

Abstract

Objective: The present study analyzed the effect of a diet with a margarine content of 52% (final concentrations of trans fats 0.104%; saturated fats 9.36%; total fats 31.2%) on the development of insulin resistance.

Materials and methods: A paired clinical study was conducted in a group of 11 Wistar rats fed a standard diet (23% protein, 3% fat, 6% fiber) and then fed a diet containing 52% trans-fat low margarine, 26% carbohydrates (provided by oat flour) and 12% protein, for 8 weeks. In both conditions, each Wistar rat was tested for insulin resistance. The area under the curve (AUC) was calculated for both diets. Results: The consumption of a diet with a high content of margarine low in trans fats increases the effect of insulin, favoring the decrease in glucose concentration in a statistically significant way (standard diet 9179 vs margarine diet low in trans fats 6663 p=0.0001).

Conclusions: Consuming a diet rich in trans-fat low-margarine promotes insulin action.

Keywords: Low trans-fat margarine; Insulin resistance; Wistar rats.

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Author Biographies

Nicté Susana Alvarado Pérez, University of Guadalajara

Student of the Faculty of Medicine. University of Guadalajara. Guadalajara, Jalisco, Mexico.
Jessica Lizeth Diez Larios, University of Guadalajara

Student of the Faculty of Medicine. University of Guadalajara. Guadalajara, Jalisco, Mexico.
Alberto Jiménez Maldonado, Autonomous University of Baja California

in Physiological Sciences. Research Professor at the Faculty of Sports. Autonomous University of Baja California. Ensenada, Baja California. Mexico.
Alin Jael Palacios Fonseca, University of Colima

Master in Chemical Sciences in the area of Food Chemistry. Research Professor. Faculty of Medicine. University of Colima. Colima. Mexico.
Mario Del Toro Equihua, University of Colima

Doctor of Medical Sciences. Research Professor. Faculty of Medicine. University of Colima. Colima. Mexico.
Joel Cerna Cortés, University of Colima

PhD in Genetics and Molecular Biology. Research Professor. Faculty of Medicine. University of Colima. Colima. Mexico.