TY - JOUR AU - Santos Muñoz, Leidy AU - Garcia-Milian, Ana Julia AU - Linares Morera, Anmy AU - Vidal Casal, Joan Javier PY - 2022/12/16 Y2 - 2024/03/29 TI - Adverse drug reactions in the elderly of Matanzas, Cuba 2014-2019 JF - Horizonte Sanitario JA - HS VL - 22 IS - 1 SE - DO - 10.19136/hs.a22n1.4996 UR - https://revistahorizonte.ujat.mx/index.php/horizonte/article/view/4996 SP - 83-88 AB - <p>Objective: To characterize suspected adverse drug reactions that<br />occurred in older adults in Matanzas, from 2014 to 2019.<br />Materials and methods: Pharmacovigilance (FV) case series study.<br />The database of reports of suspected adverse drug reactions of the<br />Provincial Pharmacovigilance Coordinating Unit, between 2014 and<br />2019, was reviewed.<br />Results: A total of 1926 reports of adverse drug reactions in the elderly<br />were evaluated, representing 24, 3% of the total. Women (56.7%) and<br />the age group between 60 and 69 years (51.4%) predominated. Skin rash<br />prevailed (13.4%). Antimicrobials and non-steroidal anti-inflammatory<br />drugs were the ones most associated with ADRs in the skin, as well as<br />in the digestive system. Cough was related to captopril. Adverse drug<br />reactions of low frequency (55.2%), moderate (83.8%) and probable<br />(77.1%) prevailed according to immutability.<br />Conclusions: The safety profile in the elderly in the province<br />of Matanzas shows a predominance of frequent, moderate and<br />probable adverse reactions in women aged between 60 and 69 years.<br />Antimicrobials, angiotensin-converting enzyme inhibitors and nonsteroidal<br />anti-inflammatory drugs were the drugs most reported by<br />doctors and pharmacists, producing symptoms at the level of the<br />digestive system and the skin.<br />Keywords: Pharmacovigilance, Adverse reactions, Elderly</p> ER -